Description
An alkaloid with diverse biological activities; inhibits AChE and BChE (IC50s = 0.51 and 6.84 µM, respectively); reduces Zika virus infection of Vero cells at 20, 40, and 80 µM; reduces colonic MPO activity and IL-10, IL-1β, IL-6, and TNF-α levels, as well as protects mucosal integrity in a mouse model of DSS-induced colitis; reduces stomach ulcer area in a rat model of acetic acid-induced gastric ulcers; reduces the number of small intestine and colon tumors in the ApcMin+/- mouse model of multiple intestinal neoplasia at 10 and 20 mg/kg